Make Use Of Lasers In A Variety Ways, Based On The Science Behind It
Safe Lasers' therapeutic value is not based on the retelling of stories, but rather a well-established scientific discipline called Photobiomodulation (PBM). PBM was once known as "low level laser therapy". It is a method that makes use of photons of laser light or superluminous diodes (SLD) to connect with the cellular components and trigger biochemical modifications. The technology employed in both the Safe Laser 1800 and 500 is engineered to leverage specific photobiological and photophysical principles. Knowing the scientific basis of this device can reveal the significance of certain parameters, like wavelength and power. It is also clear how these parameters cause an ensuing series of physiologic processes beginning on the molecular level that result in clinical benefits for the reduction of pain and healing of tissues.
1. The primary photon acquirer Cytochrome O Oxidase
Safe Laser technology's scientific foundation is based on the presence of a photoacceptor in the cell that is a primary. Numerous studies have identified cytochrome C oxidase (CCO) as a key molecule. CCO is the fourth unit of mitochondrial electron transport chains. It is a huge transmembrane complex. It is composed of metal centres (copper and heme iron), which have different spectrums of light absorption. CCO absorbs light from the near-infrared (especially the 810 nm region) and red spectrum. This absorption is able to stop the suppression of CCO by the nitric (NO) which is an oxygen deficient substance found in tissue that is inflamed. The elimination of NO makes to improve electron transfer, which in turn restores mitochondrial membrane potential.
2. The 810nm wavelength is optimized for absorption and penetration
This choice is based on scientific research. This wavelength is in the "optical or therapeutic window" for tissues, which is between 650nm and 940nm. This is a relatively small range in the sense of absorption of endogenous pigments such as hemoglobin and melanin. The laser's photons are able generated by the laser to be scattered, penetrate and reach deep tissues such as muscles, tendons ligaments or even bone. The CCO that has been oxidized CCO absorbs at 810 nm and is an extremely efficient wavelength for initiating photobiomodulation in deep tissues. This is the main target of both the SL 1800 & SL 500.
3. Power Output, Biphasic dose Response and the Arndt-Schulz Law
The biphasic response-dose relationship is the basis of PBM. This principle explains why the differences in power between the 18W and 5W models are so significant. This principle, like Arndt and Schulz Law in Pharmacology, states that very low doses of light have no noticeable effect. Moderate levels of light can stimulate, but very large amounts can cause harm. The SL 1800 does not deliver an enormous dose in one shot. It's possible to give the optimal dose (measured as Joules) within a relatively short duration, which increases the effectiveness of clinical care. The SL 500 provides the same dose over a longer period of time, which makes it ideal for localized applications or for those which are not as time-sensitive.
4. SLDs or lasers?
Safe Laser 1800 employs a pure, coherence laser diode. Coherent light, which means that all photons are in phase, is theorized to penetrate tissues more efficiently because of less scattering which is known as "superradiance." It may be possible to utilize the 1800's light more efficiently by decreasing scattering. Safe Laser 500 surrounds its central laser diode (810 nm) by a ring that contains superluminous diodes emitting 660-nm light. SLDs are monochromatic, but not coherent. The wavelength of 660 nm is absorbed in a superficial manner by hemoglobin. This makes it a suitable wavelength for skin and wound conditions. The SL 500 can target different tissues with different depths and lighting properties.
5. The Biochemical Cascade – From ATP Signaling To ROS
The first absorption of the light by CCO activates a critical biochemical cascade. The most significant result is a significant increase in Adenosine-triphosphate which is the most widely used energy currency of cells. However, the study goes beyond the energy production. The electron transport chain's enhanced activity leads to a transient minimal increase in reactive oxygen species (ROS) and the release of calcium ions. These molecules are not dangerous, but serve as signaling messengers that activate transcription factors such as NF-?B and AP-1. These molecules then transfer to the cell nucleus and increase the expression of genes linked to cell survival, proliferation and antioxidant defense.
6. Nitric Oxide (NO), Signaling and Vasodilation
Removal of nitric Oxygen from CCO by light has a two-fold advantage. First, it stimulates the mitochondria. Second NO that is released into circulation acts as a powerful vasodilator. NO relaxes smooth muscle cells in the blood vessel walls, causing them to expand. This increases local circulation increasing the nutrition and oxygenation of damaged tissue. This mechanism provides the direct connection to PBM treatment and rapid decreases in inflammation and swelling.
7. Stem Cell Multiplication and Differentiation
Evidence mounting demonstrates that PBM has the ability to influence stem cell activity. Research has demonstrated that light at 810 nm can stimulate the proliferation and migration of a variety of adult stem cells like mesenchymal stem cells (MSCs) and adipose-derived stem cells. PBM is also a factor in the differentiation pathway, promoting the transformation of osteoblasts and chondrocytes if applied properly. Safe Laser can be used to treat degenerative joint diseases and to improve bone repair.
8. Axonal Spouting and Nerve Repair
Safe Laser’s neuronal effects are at the core of its capability to treat neuropathic pain. PBM has been demonstrated to increase the expression of genes involved in neuronal growth and protection. It increases the synthesis and regeneration of proteins, such as GAP-43. The increase in ATP production is essential for nerve repair. The anti-inflammatory effects also reduce the swelling that can compress nerves, contributing to relief from pain in conditions such as carpal tunnel syndrome.
9. Cellular Redox Signaling and Antioxidant Defenses
PBM may cause mild, temporary an increase in oxidative stress. (The minor increase in ROS discussed earlier). The preconditioning stimuli triggers an adaptive response in the cell. The cell is then able to increase its powerful antioxidant defenses, including superoxide dismutase, catalase and glutathione-peroxidase. The result isn't a pro-oxidant condition, but rather an improved, more resilient cellular environment with a greater ability to face the subsequent, more serious threats to oxidation, which in turn reduces the damage to tissues that secondary to it.
10. Clinical Translation from Bench to Bedside
Safe Lasers are backed by an increasing number of peer-reviewed papers. Many laboratory studies utilizing models of animal and cell systems have uncovered the mechanisms. This science has been successfully transferred into the practice of medicine. Safe Laser 1800/500 is an application of this technology, which optimizes parameters like wavelengths, power, and the kind of application to produce reliable and predictable clinical outcomes. Follow the top rated bemer készülék for more advice including lágylézer vélemények, safe laser 500 használata, bemer nyíregyháza, safe laser vélemények, lágylézer készülék, lézeres kezelés sarkantyúra, safelaser hu, soft lézer bérlés, lágylézer terápia, lagylezer and more.
The Top 10 Side Effects Or Contraindications Of Safe Laser Devices
The non-invasiveness, safety and effectiveness of safe Laser devices is widely known However, they also serve as powerful therapeutic instruments that work with the human body. To ensure the safety of patients and efficacy, it is crucial to be aware of contraindications as well as side effects. Contraindications describe situations where an item should not be used because of the possibility of harm. The side effects can be undesirable reactions, but they're not always dangerous. A competent practitioner, or an informed person using the device at home must be able to distinguish between absolute bans and situations that require caution. This understanding is crucial to a responsible and ethical practice in the field of photobiomodulation.
1. Absolute Contraindication to Active Cancer and Malignancy
Lasers should never be utilized directly on a tumor or metastasis, regardless of whether it is suspicious or cancerous. The primary theoretical concern is that the effects of photobiomodulation–which increase cellular metabolism, growth and blood flow, could boost the growth of cancerous cells, or cause metastasis. This is an absolute prohibition. It is not allowed.
2. Direct application to the thyroid gland is an indication against.
The thyroid is very active in terms of metabolism, and it responds to stimulation. Laser energy that is applied directly to thyroid cartilage located in the neck's anterior part is strictly prohibited. The main reason is that laser energy may alter the production of thyroid hormones, or even worsen existing thyroid disorders, such as Graves' disease or thyroiditis. Although the systemic effects of treating other areas of the body are minimal by comparison, it's crucial to not focus attention on the thyroid gland.
3. Absolute contraindication pregnant women's abdomen
For the sake of safety for fetuses it is a complete contraindication to use the safe Laser on a pregnant uterus. Even though the laser is only one millimeter deep and there is no indications that harm could be caused, the principle of precaution requires that any energy not necessary to the fetus' development is to be avoided. This is an essential security measure during the three trimesters.
4. Ocular Safety: Damage to the Retinal Risk
The potential for misuse is possibly the biggest. Safe Laser devices emit a wavelength of 810nm, which is invisible. It is able to be focused on the retina by the lens by the eyes and cause thermal or photochemical damage before the user notices that it has occurred. Exposure from reflective surfaces or direct exposure should be avoided. The mandatory use of specific wavelength laser safety glasses by the operator, patient, and all other people who are in the vicinity is an essential protective measure against the serious risk of this side effect.
5. Contraindications Relative to Photosensitizing Drugs
The condition can be seen when patients are taking certain drugs. Drugs such as certain antibiotics (e.g., tetracyclines), diuretics (e.g., hydrochlorothiazide), and some antipsychotics can cause this reaction. While the risk of a reaction caused by UV light is less however, it's still a contraindication. A complete medication review of the patient is necessary. A patch test or a treatment with a lower dosage could be advisable.
6. The "Healing Crisis", also known as the "Crisis of Repair" is a time of healing.
A possible, but often unnoticed adverse effect can be a temporary exacerbation of symptoms after the first treatment. Known as a "healing crisis" it isn't an indication of damage, instead, it's a heightened stimulation of the body's inflammatory and repair mechanisms. As circulation improves, and cellular debris begins to be eliminated, a few sufferers may experience an increased swelling, pain or stiffness. The majority of the time, this will resolve within 24 to 48 hours. By educating your patients, you can prevent unnecessary worry and even treatment discontinuation.
7. Hemorrhage Disorders and Coagulation Disorders Relative contraindications
A major, acute hemorrhage shouldn't be treated using the PBM laser due to its vasodilatory nature (caused predominantly by nitric acids release). This may theoretically result in more bleeding during the initial stages. In patients with severe hemophilia or who are receiving high doses of anticoagulant medications are prescribed but the treatment must be given after consultation with a doctor.
8. Lack of Sensation & Over-treatment Risk
Safe Laser Therapy is distinctive in that it does not cause a sensation of heat when it is applied properly. The most often reported negative side consequence is "no sensation." It can be the potential to be a double-edge. If a patient doesn't have the proper knowledge or training to adhere to the dose may believe that the device isn't functioning, and thus over-treat an part. The biphasic reaction could result in a decrease in therapeutic effect.
9. Special Patient Populations: Precautions
Certain populations require special consideration. For children and teens applying direct lasers with high energy to the epiphyseal or growth plates in long bone should be avoided since it is not known what impact it will have on bone growth. Because it's non-thermal, it's not a high risk but it's still an excellent idea to avoid placing the laser directly over the heartbeat generator or any other electronic device.
10. Skin Reactions and Endogenous Photosensitivity
The presence of a true adverse skin reaction is extremely rare. Certain people may experience a brief redness (erythema) because of the increase in blood flow. This is a normal and desired result, not a negative consequence. The light is not likely to trigger any allergic reactions. In the case of drugs that cause photosensitization, certain conditions like porphyria lupus or other exogenous conditions can cause increased sensitivity to different wavelengths. To ensure that these conditions are identified and treated with the appropriate caution, a patient's history must be thoroughly examined. View the top Safe Laser 500; for blog examples including soft lézer kezelés ára, fizioterápia lézeres kezelés, lézeres fizikoterápia, lézer kezelés vélemények, soft laser készülék, soft lézer kezelés budapest, lágylézer ár, széf lézer, orr lézer készülék, safe laser 1800 vélemények and more.
